Pepperoni Pizza Casserole Recipe -

Pepperoni Pizza Casserole Recipe

Pepperoni Pizza Casserole is a fun and tasty twist on traditional pizza, perfect for pizza lovers looking for a hearty and comforting meal. This casserole layers all the beloved elem

ents of a pepperoni pizza, including gooey cheese, zesty tomato sauce, and savory pepperoni, with pasta to create a filling and satisfying dish. It’s ideal for family dinners, potlucks, or any occasion when you crave the flavors of pizza in a more substantial form.


  1. 1 pound pasta (such as rotini, penne, or rigatoni)
  2. 1 tablespoon olive oil
  3. 1 medium onion, chopped
  4. 2 cloves garlic, minced
  5. 1 pound ground beef or Italian sausage
  6. 1 jar (24 ounces) marinara sauce
  7. 1 package (3.5 ounces) pepperoni slices
  8. 2 cups shredded mozzarella cheese
  9. 1 cup shredded cheddar cheese
  10. 1 teaspoon dried oregano
  11. Salt and pepper to taste
  12. Fresh basil, chopped (for garnish)



Step 1: Cook the Pasta

  • Preheat your oven to 375°F (190°C).
  • Cook the pasta according to package instructions until al dente. Drain and set aside.

Step 2: Prepare the Meat Sauce

  • In a large skillet, heat the olive oil over medium heat. Add the onion and garlic and sauté until softened.
  • Add the ground beef or Italian sausage to the skillet. Cook until browned, breaking it up with a spoon. Drain excess fat.
  • Stir in the marinara sauce and bring to a simmer. Season with oregano, salt, and pepper.

Step 3: Assemble the Casserole

  • In a large baking dish, spread a layer of the meat sauce.
  • Add a layer of cooked pasta, then a layer of pepperoni slices, followed by a layer of mozzarella and cheddar cheeses.
  • Repeat the layers, finishing with a layer of cheese and pepperoni on top.

Step 4: Bake the Casserole

  • Cover the baking dish with foil and bake for 25 minutes.
  • Remove the foil and bake for an additional 10-15 minutes, or until the cheese is melted and bubbly.

Step 5: Serve

  • Let the casserole cool for a few minutes before serving.
  • Garnish with chopped fresh basil.



Cooking Note:

  • You can adjust the amount of cheese and pepperoni to suit your taste.

Serving Suggestions:

  • Serve the Pepperoni Pizza Casserole with a side salad, garlic bread, or steamed vegetables for a complete meal.


  • For a healthier version, use whole wheat pasta and turkey pepperoni.
  • Feel free to add other pizza toppings like mushrooms, bell peppers, or olives to the layers.

Prep Time: 20 minutes Cooking Time: 40 minutes Total Time: 1 hour

Nutritional Information:

  • Calories: Approximately 400-450 per serving
  • Protein: 25g
  • Sodium: 700mg

Conclusion: Pepperoni Pizza Casserole is a delightful and hearty dish that’s perfect for those who love pizza and are looking for a comforting, oven-baked meal. It’s a versatile recipe that can be customized with your favorite pizza toppings, making it a crowd-pleaser for both kids and adults.

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